How scientists solved in only ten days complex protein structure with co-creation and gamification
Here’s a great talk by Seth Cooper and Firas Khatib (University of Washington) who describe the massive possibilities of crowdsourced games like Foldit (“Solve Puzzles for Science“) at TEDx Panthéon Sorbonne. Foldit, which results from part of an experimental research project from the University of Washington, is an online puzzle video game about protein folding centered around folding the structure of selected proteins to the best of the player’s ability (see it in action in this video).
It received big coverage recently when Foldit gamers have helped unlock the structure of an AIDS-related enzyme that the scientific community had been unable to unlock for a decade. The resulting research paper, Crystal structure of a monomeric retroviral protease solved by protein folding game players (PDF), has been published in Nature and is co-authored by the participating Foldit teams “Foldit Contenders Group” and “Foldit Void Crushers Group.” A…
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